Keeble’s career highlights include Dritte Dame Die Zauberflöte and The Voice of Antonia’s Mother Les Contes d’Hoffmann (Royal Opera House); Annina La Traviata (Royal Opera House & Welsh National Opera); Marcellina Le nozze di Figaro (Opera North, Welsh National Opera, English Touring Opera); Dame Carruthers The Yeomen of the Guard, Katisha The Mikado (English National Opera); Gertrude Roméo et Juliette, Mother/Witch Hansel and Gretel, Hippolyta A Midsummer Night’s Dream, and Dame Hannah Ruddigore (Opera North); Berta Il barbiere di Siviglia, The Councillor’s Wife Osud, and Ragonde Comte Ory (Welsh National Opera); Auntie Peter Grimes (Aldeburgh Festival, Grimes on the Beach); Florence Pike Albert Herring (BBC Symphony Orchestra); Mrs Sedley Peter Grimes (City of Birmingham Symphony Orchestra); Baba the Turk The Rake’s Progress, Marquise de Birkenfeld La Fille du Régiment, and Lady Angela Patience (English Touring Opera); Kostelnicka Jenufa (Longborough Festival Opera); Dritte Dame Die Zauberflöte (Dorset Opera); Dame Hannah Ruddigore, Queen of the Fairies Iolanthe, and Lady Blanche Princess Ida (Harrogate International Festival); Marquise de Birkenfeld La Fille du Régiment and Mistress Quickly Falstaff (Switzerland & France); subsequent roles include Ludmilla The Bartered Bride, Larina Eugene Onegin, Madam Popova The Bear, and Mere Jeanne Dialogue des Carmélites.

Concert appearances include performances with the BBC Symphony Orchestra; City of Birmingham Symphony Orchestra; the Philharmonia; the Royal Philharmonic Orchestra; the London Mozart Players; the Northern Sinfonia and the RTÉ Concert Orchestra with conductors such as Sir Charles Mackerras, Sir Colin Davis, Nicola Luisotti, Alexander Joel, Dan Ettinger, Julia Jones, Sakari Oramo, and Steuart Bedford. Her recordings include Lady Bellaston in Edward German’s Tom Jones (Naxos); Councillor’s Wife Osud (EMI); HMS Pinafore, Patience and The Yeomen of the Guard (TER Classics); and Auntie Peter Grimes (Signum Classics).